Melissus, the son of Ithaegenes, was a native of Samos. He was a pupil of Parmenides. Moreover he came into relations with Heraclitus, on which occasion the latter was introduced by him to the Ephesians, who did not know him as Democritus was to the citizens of Abdera by Hippocrates. He took part also in politics and won the approval of his countrymen, and for this reason he was elected admiral and won more admiration than ever through his own merit.
In his view the universe was unlimited, unchangeable and immovable, and was one, uniform and full of matter. There was no real, but only apparent, motion. Moreover he said that we ought not to make any statements about the gods, for it was impossible to have knowledge of them.
According to Apollodorus, he flourished in the 84th Olympiad.